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Review of the first 20 years of the Evidence‐Based Medicine Committee of the Japan Society
Yoshiharu Motoo et al.
Published on: 5/8/2021
The Evidence‐Based Medicine Special Committee of the Japan Society for Oriental Medicine was launched in 2001. We summarize the task force‐specific activities of this committee over the past 20 years.
Knowledge Dissemination by the Naturopathic Profession: A Bibliometric Analysis of Naturopath
Amie Steel et al.
Published on: 5/7/2021
This study aims to describe the characteristics of published peer-reviewed journal articles authored by naturopathic practitioners (NPs).
Barriers and Facilitators to Integrative Oncology Services in Australia: A Changed Mind Set Required
Jennifer Hunter et al.
Published on: 5/6/2021
This study aimed to explore barriers and facilitators to integrative oncology (IO) service provision and access in Australia.
Effects of Acupuncture on Lowering Blood Pressure in Postmenopausal Women with Prehypertension
Bok-Nam Seo et al.
Published on: 5/5/2021
Postmenopausal women have a higher prevalence of hypertension compared to premenopausal women. Hypertension is a risk factor for cardiovascular diseases, the prevalence of which is ever increasing. This study investigated the effects of long-term acupuncture on lowering the blood pressure of postmenopausal women with prehypertension and stage 1 hypertension.
Stakeholder Attitudes to the Regulation of Traditional and Complementary Medicine Professions
Jenny Carè et al.
Published on: 5/3/2021
There has been a considerable increase in the number of traditional and complementary medicine (T&CM) practitioners over the past 20 years and in some jurisdictions are estimated to outnumber general practitioners. Despite this globally significant role, it is apparent that worldwide not all T&CM professions operate under adequate accountability and regulatory oversight for maintaining public protection. To date there has been no published systematic examination of stakeholder opinions regarding regulated and unregulated T&CM occupations. In response, this review aims to investigate, describe, and analyse attitudes held by a range of stakeholder groups towards the regulation of T&CM professions.
Fasting Alters the Gut Microbiome Reducing Blood Pressure and Body Weight in Metabolic Syndrome
András Maifeld et al.
Published on: 5/2/2021
Periods of fasting and refeeding may reduce cardiometabolic risk elevated by Western diet. Here we show in the substudy of NCT02099968, investigating the clinical parameters, the immunome and gut microbiome exploratory endpoints, that in hypertensive metabolic syndrome patients, a 5-day fast followed by a modified Dietary Approach to Stop Hypertension diet reduces systolic blood pressure, need for antihypertensive medications, body-mass index at three months post intervention compared to a modified Dietary Approach to Stop Hypertension diet alone.
Efficacy and Safety of Qiming Granule Combined With Laser in the Treatment of Diabetic Retinopathy
Chuiren Zhou et al.
Published on: 5/1/2021
Diabetic retinopathy is not only the most common complication of diabetes, but also 1 of the main causes of blindness, which seriously affects the physical and mental health of patients. Panretinal photocoagulation is a common method for the treatment of diabetic retinopathy, but it has some defects. Qiming granule has advantages in the treatment of diabetic retinopathy, but there is a lack of standard clinical research to verify it. Therefore, the purpose of this randomized controlled trial is to evaluate the efficacy and safety of qiming granule combined with laser in the treatment of diabetic retinopathy.
Cupping Therapy for Migraine: A PRISMA-Compliant Systematic Review and Meta-Analysis of Randomized
Jihye Seo et al.
Published on: 4/30/2021
Migraine is a common reason for primary headache disorders. Cupping is a frequently used traditional intervention for controlling pain including migraine. There have been no systematic reviews on the clinical effects of cupping on migraine.
Addressing Complementary and Alternative Medicine Use Among Individuals With Cancer: an Integrative
Lynda G. Balneaves et al.
Published on: 4/29/2021
Complementary and alternative medicine (CAM) use is common among individuals with cancer, but many choose not to discuss CAM with healthcare providers (HCPs). Moreover, there is variability in the provision of evidence-informed decision making about CAM use. A clinical practice guideline was developed to standardize how oncology HCPs address CAM use as well as to inform how individuals with cancer can be supported in making evidence-informed decisions about CAM.
Acupuncture Research in Animal Models: Rationale, Needling Methods and the Urgent Need
Ari Ojeda Ocampo Moré et al.
Published on: 4/27/2021
Basic science research in general, and acupuncture mechanisms research in particular, is vulnerable to criticism regarding the reproducibility of animal results, as well as their clinical translation. A critical tool for addressing challenges of reproducibility in research is the use of guidelines such as the Consolidated Standards of Reporting Trials (CONSORT) checklist for reporting clinical research.
Eye Acupuncture for Pain Conditions: A Scoping Review of Clinical Studies
Yuan Chi et al.
Published on: 4/25/2021
Chinese eye acupuncture, focuses on treating different diseases by applying needle stimulation around the orbit of the eye. Since 1970, it has been used in China for the management of pain-related disorders. This scoping review systematically collected clinical studies on the use of eye acupuncture to treat pain conditions and identify any adverse events.
Assessing the Quality of Information Provided on Websites Selling Kratom (Mitragyna speciosa)
Jeremy Y. Ng et al.
Published on: 4/23/2021
Amid a Canadian opioid crisis, many have turned to natural health products, such as kratom (Mitragyna speciosa), to manage their opioid withdrawal. Kratom has also been reported to relieve anxiety, improve stamina, and heighten physical performance. Given that kratom is not authorized for sale by Health Canada, many have turned to online retailers to purchase kratom due to its easy accessibility online. This study investigated the quality of consumer health information provided on the websites of online vendors selling kratom to consumers in Canada.
Elicitation of Stakeholder Viewpoints about Medical Cannabis Research for Pain Management
Giulio DiDiodato et al.
Published on: 4/21/2021
To determine acceptability of medical cannabis research in critically ill patients.
Effectiveness and Safety of Electroacupuncture in Treating Parkinson Disease: A Protocol
Xu Wei et al.
Published on: 4/19/2021
Parkinson disease (PD) is an Extrapyramidal Disease mainly characterized by static tremor, myotonia, bradykinesia and postural gait disorder. As China's population ages, the number of people suffering from PD is increasing. Since there are many side effects of western medicine for Parkinson's patients, and the high price of the drugs make it difficult for many patients to adhere to treat. At present, many clinical studies have shown that electroacupuncture is effective in treating PD. Therefore, this systematic review aims to explore the effectiveness and safety of electroacupuncture in the treatment of PD.
Clinical Acupuncture Therapy for Chronic Cholecystitis: A Protocol for Systematic Review
Genping Zhong et al.
Published on: 4/19/2021
Chronic cholecystitis is a common chronic disease in clinical practice. The incidence of chronic cholecystitis is gradually increasing due to changes in eating habits and even if acute infections aren’t treated in time, it can cause serious complications, continue to plague people's daily life and become an economic burden to society. Currently, the curative effect of chronic cholecystitis under the control of western medicine is still lacking and there are adverse reactions. However, based on current clinical controlled trials acupuncture therapy for chronic cholecystitis has gradually become a complementary treatment. Therefore, this systematic review aims to explore the safety and feasibility of acupuncture therapy in the treatment of chronic cholecystitis.
Gualou Guizhi Granule Protects against OGD/R-Induced Injury by Inhibiting Cell Pyroptosis
Yuqin Zhang et al.
Published on: 4/17/2021
Pyroptosis is a proinflammatory form of regulated cell death that plays an important role in ischemic stroke. Gualou Guizhi granule (GLGZG) is a classic prescription that has been shown to exert neuroprotective effects against cerebral ischemia reperfusion injury. In the present study, we examined the involvement of pyroptosis and its associated mechanism in protecting nerve function. Methods. Primary neurons were exposed to oxygen-glucose deprivation and reperfusion (OGD/R) conditions in the presence or absence of GLGZG.
The Effectiveness and Safety of Chuna Manual Therapy on Scoliosis: A Protocol for Systematic Review
Seo-Hyun Park et al.
Published on: 4/15/2021
Scoliosis is a spinal deformity and is diagnosed as Cobb angle being greater than 10°. Because it is accompanied with structural dysfunction, it can cause pain, worsen the patient's general health and quality of life. The prevalence of scoliosis has been increasing and many treatments, including surgical treatment and conservative treatment, such as observation, bracing, physiotherapy, and Chuna manual therapy (CMT), have been suggested. CMT is a manual therapy in Korean medicine that provides effective stimulation to the patient's body structure to treat structural dysfunction. After Korean national health insurance's coverage of CMT in 2019, the application of CMT for scoliosis has increased, and many studies have been reported. There have been attempts to elucidate the effectiveness of CMT on scoliosis; however, its effectiveness still remains unconfirmed. Therefore, the aim of this study is to evaluate the effectiveness and safety of CMT on scoliosis.
Designing Delivery Models of Traditional and Complementary Medicine Services: A Review
Vincent C H Chung et al.
Published on: 4/13/2021
The World Health Organization advocates integration of traditional and complementary medicine (T&CM) into the conventional health services delivery system. Integrating quality services in a patient-centred manner faces substantial challenges when T&CM is delivered within a health system dominated by conventional medicine. This review has synthesized international experiences of integration strategies across different contexts.
Are Supplemental Branched-Chain Amino Acids Beneficial During the Oncological Peri-Operative Period
Elise Cogo et al.
Published on: 4/11/2021
Branched-chain amino acids (BCAAs; leucine, isoleucine, and valine) are essential amino acids involved in immune responses, and may have roles in protein malnutrition and sarcopenia. Furthermore, certain liver diseases have been associated with a decreased Fischer’s ratio (BCAAs to aromatic amino acids; phenylalanine, tyrosine, and tryptophan). We aimed to evaluate the safety and efficacy of BCAAs use in patients with cancer undergoing surgery.
Complementary and Integrative Medicine: An Observational Study on Pediatric Clinicians’ Knowledge
Nicole Casbarro et al.
Published on: 4/9/2021
Complementary and Integrative Medicine (CIM) is a group of diverse health care therapies that often serve as adjuncts to conventional medical treatments. Our aim for this study was to evaluate the current knowledge, beliefs and practices of pediatric clinicians regarding CIM.
Adjuvant Melatonin for the Prevention of Recurrence and Mortality Following Lung Cancer Resection
Dugald Seely et al.
Published on: 4/7/2021
Despite curative intent resection in patients with non-small cell lung cancer (NSCLC), recurrence leading to mortality remains too common. Melatonin has shown promise for the treatment of patients with lung cancer; however, its effect following cancer resection has not been studied. We evaluated if melatonin taken after complete resection reduces lung cancer recurrence and mortality, or impacts quality of life (QOL), symptomatology or immune function.
The Use and Benefits of Craniosacral Therapy in Primary Health Care: A Prospective Cohort Study
Heidemarie Haller et al.
Published on: 4/5/2021
Patients frequently use treatments complementary to standard primary care. This prospective cohort-study examined the use, benefits, and safety of Craniosacral Therapy (CST).
The Effect of a Complementary Therapy Education Seminar on Support Persons of Individuals
Nancy Allen Searson et al.
Published on: 4/3/2021
Complementary therapy (CT) use is prevalent among individuals living with cancer, who often consult family and friends (i.e., support persons) in making decisions about CT. This study examines the effect of an education seminar for adult cancer patients and support persons on the support persons' use, knowledge, and decision-making processes related to CT.
Effectiveness and Safety of Acupuncture in the Treatment of Chronic Severe Functional Constipation
Daocheng Zhu et al.
Published on: 4/1/2021
Acupuncture has been widely used clinically to relieve chronic severe constipation. However, the efficacy of acupuncture in the treatment of chronic severe constipation is uncertain. The purpose of this study is to determine the effectiveness and safety of acupuncture in the treatment of chronic severe constipation.
The Presence of Complementary and Alternative Medicine Recommendations in Head and Neck Cancer
Jeremy Y. Ng et al.
Published on: 3/31/2021
A high proportion of head and neck cancer (HNC) patients use complementary and alternative medicine (CAM), however, healthcare professionals generally have little knowledge about the safety and efficacy of these therapies. The purpose of this study was to determine the quantity and assess the quality of CAM recommendations across clinical practice guidelines (CPGs) for the treatment and/or management of HNC.
International Policies and Challenges on the Legalization of Traditional Medicine/Herbal Medicines
Yin Xiong et al.
Published on: 3/29/2021
The coronavirus disease 2019 (COVID-19) has now rapidly spread around the world, causing an outbreak of acute infectious pneumonia. To develop effective and safe therapies for the prevention and treatment of COVID-19 has become the major global public health concern.
A Comparison of the Effect of Topical Preparation of Sambucus ebulus L. and Hydrocortisone on Hand
Akram Moradi Farahani et al.
Published on: 3/27/2021
Corticosteroids as the main treatment of hand eczema can cause major side effects. This study compared the effect of topical preparation of Sambucus ebulus L. leaves and hydrocortisone on the severity of hand eczema.
The Effectiveness and Safety of T-MSAT on Inpatients with Acute Low Back Pain Caused by Traffic
Jeong-Hun Han et al.
Published on: 3/25/2021
Presentation of musculoskeletal symptoms, such as pain, discomfort, or disability, caused by a traffic accident (TA) is a common occurrence. However, studies on treatment and management of sudden low back pain (LBP) caused by a TA are very scarce, while studies on the effectiveness of motion style acupuncture therapy (MSAT) used on such patients are also rare. Accordingly, a randomized controlled trial (RCT) is planned to assess the effectiveness and safety of MSAT using traction (T-MSAT) for the treatment of pain and functional problems in patients with acute LBP caused by a TA.
Integrative Oncology Education: An Emerging Competency for Oncology Providers
Safiya Karim et al.
Published on: 3/23/2021
A growing number of cancer patients use complementary and alternative therapies during and after conventional cancer treatment. Patients are often reluctant to discuss these therapies with their oncologist, and oncologists may have limited knowledge and confidence on how to advise patients on the appropriate use.
A Systematic Review and Quality Assessment of Complementary and Alternative Medicine Recommendations
Jeremy Y. Ng et al.
Published on: 3/21/2021
Sleep disorders encompass a wide range of conditions which affect the quality and quantity of sleep, with insomnia being a specific type of sleep disorder of focus in this review. Complementary and alternative medicine (CAM) is often utilized for various sleep disorders. Approximately 4.5% of individuals diagnosed with insomnia in the United States have used a CAM therapy to treat their condition. This systematic review identifies the quantity and assesses the quality of clinical practice guidelines (CPGs) which contain CAM recommendations for insomnia.
Complementary and Alternative Medicine Mentions and Recommendations in Glaucoma Guidelines
Jeremy Y. Ng et al.
Published on: 3/19/2021
Glaucoma is one of the leading causes of irreversible vision loss and blindness. The global prevalence of glaucoma is 3.54% of the population aged 40–80 years old. Glaucoma and its associated symptoms are often self-medicated using CAM therapies. This study aims to determine the quantity and quality of CAM recommendations within clinical practice guidelines (CPGs) for the treatment and/or management of glaucoma.
Complementary Medicine Students’ Perceptions, Perspectives and Experiences of Learning Technologies
Alastair C. Gray et al.
Published on: 3/18/2021
The education of complementary medicine (CM) practitioners has received little research attention even though CM occupies a significant role in the Australian and US healthcare systems and the CM education sector continues to grow and professionalise. The objective of this study was to explore the perceptions of CM students to learning technologies.
Development and Preliminary Evaluation of the Conventional Medicine Disclosure Index
Erica McIntyre et al.
Published on: 3/15/2021
Non-disclosure of conventional medicine use to complementary medicine health professionals may result in patient harm. Currently, no standardised validated instrument is available to measure reasons for conventional medicine disclosure or non-disclosure.
Effect of Honey–Lemon Spray Versus Benzydamine Hydrochloride Spray on Radiation-Induced Acute Oral
Ahmad Ameri et al.
Published on: 3/13/2021
Oral mucositis (OM) is the most prevalent side effect in patients with head and neck cancer (HNC). It causes an obvious decrease in quality of life (QoL) in these patients, so different medications have been recommended for OM, however, without optimal response. This randomized trial aimed to assess the effects of a honey–lemon spray compared with benzydamine hydrochloride in prevention of radiation-induced OM in patients with HNC.
The Quality of Information Available about Ephedra sinica on Online Vendor Websites: The Canadian
Jeremy Y. Ng et al.
Published on: 3/11/2021
Ephedra sinica (ES) is a natural health product used to promote weight loss, enhance athletic performance, and treat common ailments such as the common cold or flu. Due to restrictions within Canada, Canadians interested in purchasing this product turn to online vendors for the ease and discrete nature of online transactions. However, the information available on these websites for consumers looking to purchase the substance is variable. This study investigated the quality of information about ES available to Canadian consumers on the websites of these online vendors.
Quyu Shengji Formula Facilitates Diabetic Wound Healing via Inhibiting the Expression
Yi Lu et al.
Published on: 3/9/2021
Quyu Shengji Formula (QSF), a Chinese medicine formula widely used in the clinic, has proven therapeutic effects on diabetic ulcers. Nevertheless, the potential mechanism of how QSF cures diabetic ulcer remains elusive.