Researchers of Traditional, Complementary, Alternative, & Integrative Medicine and Health

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Identification of Glycyrrhizin Metabolites in Humans and of a Potential Biomarker of Liquorice-Induced Pseudoaldosteronism: A Multi-Centre Cross-Sectional Study

Liquorice [main ingredient, glycyrrhizin (GL)] is widely used as a food sweetener and herbal medicine. Occasionally, liquorice consumption causes pseudoaldosteronism as a side effect which causes oedema, hypokalaemia, and hypertension due to hyperactivity of mineral corticoid receptor. We aimed to detect GL metabolites in human blood and urine samples and to determine the pathological relationship between GL metabolites and pseudoaldosteronism. Read more here.