Safety, Effectiveness, and Economic Evaluation of an Herbal Medicine, Ukgansangajinpibanha Granule, in Children with Autism Spectrum Disorder: A Study Protocol for a Prospective, Multicenter, Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group
Autism spectrum disorder (ASD) is characterized by continuous impairment in communication and social interaction and by limited and repetitive behaviors, interests, or activities. Behavioral, educational, and pharmaceutical interventions have been shown to reduce behavioral disabilities, improve verbal/non-verbal communication, and help patients acquire self-reliance skills. However, there has been a lack of systematic verification and consensus regarding the treatment of the core symptoms of ASD because of its unclear etiology. Ukgansangajinpibanha (UGSJB), a legitimately prescribed herbal medicine for nervousness, insomnia, night crying, and malnutrition in South Korea and Japan, has been used for angry, sensitive, nervous, and unsettled children with ASD. Read more here.