Researchers of Traditional, Complementary, Alternative, & Integrative Medicine and Health

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2-Aminobutyric Acid Modulates Glutathione Homeostasis in the Myocardium

A previous report showed that the consumption of glutathione through oxidative stress activates the glutathione synthetic pathway, which is accompanied by production of ophthalmic acid from 2-aminobutyric acid (2-AB). We conducted a comprehensive quantification of serum metabolites using gas chromatography-mass spectrometry in patients with atrial septal defect to find clues for understanding myocardial metabolic regulation, and demonstrated that circulating 2-AB levels reflect hemodynamic changes. However, the metabolism and pathophysiological role of 2-AB remains unclear.

Effects of Omega-3 Polyunsaturated Fatty Acids on Human Brain Morphology and Function: What is the Evidence?

Public opinion and media coverage suggest that there are benefits of long-chain ω-3 polyunsaturated fatty acid (LC-PUFA) intake on brain functioning. However, it is an open question whether this is indeed the case. Therefore, we reviewed the evidence for effects of ω-3 LC-PUFA on human brain morphology and function.

Effects of Ginkgo Biloba on Dementia: An Overview of Systematic Reviews

To assess the cumulative evidence on the efficacy and effectiveness of Ginkgo biloba extract (GbE) in the treatment of dementia. Read more here.

Reduced Allergic Lung Inflammation by Root Extracts from Two Species of Peucedanum through Inhibition of Th2 Cell Activation

Peucedani Radix (PR), the root of Peucedanum praeruptorum Dunn (PPD) or Peucedanum decursivum (Miq.) Maxim. (PDM), has long been used in Korea to eliminate sputum, relieve cough, and reduce bronchus contraction. Furthermore, these therapeutic strategies are recognized as general and effective methods in western medicine as well as traditional Korean medicine. Read more here.

Mindfulness Interventions for Psychosis: A Systematic Review of the Literature

A growing number of mindfulness interventions are being used with individuals with psychosis. These therapies employ elements of acceptance and compassion in addition to mindfulness. A number of randomized controlled trials (RCTs) of these interventions have emerged in recent years, but no review of these latest trials exists. Read more here.

Effect of Ocimum gratissimum in Mouthrinses on De Novo Plaque Formation. A Randomized Clinical Trial

The aim of this study was to evaluate the antiplaque effect of Ocimum gratissimum (Og) by in vivo investigation. Fifteen healthy volunteers participated in a crossover, double-blind clinical study, using a 3-day partial-mouth plaque accumulation model. The participants abolished any method of mechanical oral hygiene and they were randomly assigned to initially use just the following mouthrinses: distilled water (DW solution), 0.12% chlorhexidine digluconate (CLX solution) or 10% Og (Og solution).

Outcomes from a Three-Arm Randomized Controlled Trial of Frequent Immersion in Thermoneutral Water on Cardiovascular Risk Factors

Cardiovascular diseases are a main cause of mortality worldwide. Spa bathing and immersion in thermoneutral water (ITW) have a long history in the treatment of cardiovascular risk factors. Read more here.

Complementary and Alternative Medicine for Nausea and Vomiting

Complementary and alternative medicines (CAM) are commonly used in the general population, often without involvement of physicians. This chapter is devoted to describing some common and safe complementary and alternative therapies for nausea and vomiting, with discussions on possible mechanism of action and review of the current literature. This chapter aims to aid in closing the gap between patients’ and physicians’ perceptions around CAM. Read more here.

Anti-inflammatory and In-vitro Antibacterial Activities of Traditional Chinese Medicine Formula Qingdaisan

Qingdaisan (Formulated Indigo powder, QDS) are widely used for treatment of aphtha, sore throat and bleeding gums in China. The aim of the study is to evaluate the anti-inflammatory, antibacterial and dental ulcer therapeutic effects of QDS. Read more here.

A Scoping Review on Models of Integrative Medicine: What Is Known from the Existing Literature?

Integrative medicine (IM) has been recognized and introduced into Western healthcare systems over the past two decades. Limited information on IM models is available to guide development of an optimal healthcare service. A scoping review was carried out to evaluate IM models in the extant literature, including the distinctive features of each model, to gain an understanding of the core requirements needed to develop models of IM that best meet the needs of patients. Read more here.

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